Abstract Poster Wall

2026 Kidney Cancer Research Summit

Abstract 24

A phase 1b/2 study of abemaciclib plus cabozantinib in immune checkpoint blockade-pretreated metastatic clear cell renal cell carcinoma and translocation-associated renal cell carcinoma

Sahil Doshi

Abstract 26

Outcomes of Systemic Therapy in Metastatic Translocation Renal Cell Carcinoma (tRCC): A Mayo Clinic Retrospective Study

Oluwatayo Adeoye

Abstract 31

Racial demographic reporting in clinical trials informing NCCN kidney cancer guidelines

Suhail Sapkota

Abstract 32

Inflamed eosinophilic phenotype predicts improved outcomes without excess immune-related adverse events in first-line ICI-treated metastatic renal cell carcinoma

Jack Masur

Abstract 33

Plasma proteomic profiling reveals SEZ6L2 as a novel biomarker in translocation renal cell carcinoma

Shane Killarney

Abstract 34

Belzutifan plus lenvatinib versus cabozantinib in post–PD-(L)1 renal cell carcinoma: Health-related quality-of-life outcomes in the phase 3 LITESPARK-011 study

Rodolfo Perini

Abstract 35

Targeting HIF2-driven Endogenous Retroviral Antigens for Immunotherapy in Kidney Cancer

Qinqin Jiang

Abstract 36

Clear cell renal cell carcinoma consensus transcriptomic programs reveal converging trajectories towards aggressive disease

Roy Elias

Abstract 37

Deciphering the Genomic Landscape of Renal Cell Carcinoma Brain Metastases

Betul Gok Yavuz

Abstract 38

Prognostic Nutritional Index as a Predictor of Outcomes with Immune Checkpoint Inhibitors in Renal Cell Carcinoma

Kashyap Koul

Abstract 39

NPRL2 Expression Associates with Cytotoxic Immune Function Independent of Estimated Immune Cell Abundance in TCGA-KIRC

Muhammed Onel

Abstract 40

Ferritin-Dependent Iron Storage and Ferritinophagy Impact Ferroptosis Sensitivity in Chromophobe Renal Cell Carcinoma

Wafaa Bzeih

Abstract 41

Clinical Utility of Ultrasensitive ctDNA Detection Across the Renal Cell Carcinoma Disease Spectrum: A Multi-Cohort Retrospective Study

Ezra Blumenthal

Abstract 44

Ferroptosis Suppressor Protein 1 (FSP1) Drives Ferroptosis Resistance in Chromophobe Renal Cell Carcinoma

Steven Safi

Abstract 46

TKI resistance is associated with immune dysfunction in ccRCC

Xiande Liu

Abstract 47

Hemoglobin Drop Is An Early Predictor Of Erythropoietin Supplementation In VHL Syndrome Patients Under Belzutifan Treatment – First Report From The Real-Life BELIEVE-VHL Trial

Jose Claudio Casali-da-Rocha

Abstract 49

Effect of co-morbidity burden on the efficacy and tolerability of belzutifan in patients with metastatic renal cell carcinoma

Ali Hajj Ali

Abstract 50

Tumor–myeloid multicellular programs reveal ECM-associated macrophage polarization in ccRCC

Katsuhiro Ito

Abstract 51

Discovery of exhausted CD8+ T-cell states associated with clinical outcomes in renal cell carcinoma

Zhaochen Ye

Abstract 52

FGD1 Splice Variant in Clear Cell Renal Cell Carcinoma is a Novel Biomarker for Inferior Clinical Outcomes and Development of Brain and Bone Metastases.

Brandon Manley

Abstract 53

Neprectomy remodels peripheral myeloid cell states in renal cell carcinoma

Stephanie Schwartz

Abstract 55

Renal Cell Carcinoma tumor interstitial fluid possesses immunosuppressive and GPCR activating properties

Colin Laughlin

Abstract 57

Final Analysis of the TiNivo-2 Phase 3 Trial: Long-term Outcome of Tivozanib (Tivo) in patients with metastatic renal cell carcinoma (mRCC)

Bradley McGregor

Abstract 58

Baseline peripheral TCR diversity as a biomarker of response to first-line immunotherapy in metastatic clear cell renal cell carcinoma

Luigi Roca

Abstract 60

Germline platelet polygenic risk score predicts renal cell carcinoma survival via sustained thrombocytosis

Mustafa Saleh

Abstract 61

Differential Pattern of Disease Recurrence in Resected Renal Cell Carcinoma Patients Treated with Adjuvant Pembrolizumab versus Observation: A Propensity Score-Weighted Analysis

Liliana Ascione

Abstract 62

Patient Experience with Clinical Trials: Results from the International Kidney Cancer Coalition Global Patient Survey

Eric Jonasch

Abstract 64

GPR65 is a Novel Therapeutic Target Associated with Immune Exhaustion in Clear Cell Renal Cell Carcinoma

Nicholas Salgia

Abstract 66

Relationship between health-related quality of life and efficacy in the phase 3 LITESPARK-005 study of belzutifan versus everolimus in previously treated advanced clear cell renal cell carcinoma

Pooja Ghatalia

Abstract 67

Foundation model embeddings identify spatial restructuring associated with immunotherapy treatment derived from hemoxylin and eosin images

Alex Soupir

Abstract 68

LNK001 is a high-fidelity AND-logic-gated CAR T cell therapy that enables precision targeting of clear cell Renal Cell Carcinoma (ccRCC): Target discovery and validation for the ATHENA Phase 1 trial

Alexander Bankovich

Abstract 69

Spatial Proteomics Profiling Identifies Prognostic Biomarkers in Papillary Renal Cell Carcinoma

Jared Brewer

Abstract 70

Lymphocyte Hsp70 is a novel predictive biomarker for response to immune checkpoint inhibitors in metastatic renal cell carcinoma

Ethan Burns

Abstract 72

Time-of-day of immune checkpoint inhibitor infusion and overall survival in renal cell carcinoma: a real-world cohort analysis

Pablo Barrios

Abstract 75

Transcriptional correlates of ARNT expression and its impact on survival outcomes in clear-cell renal cell carcinoma (ccRCC)

Wassim Daoud Khatoun

Abstract 76

Defining Young-Onset Renal Cell Carcinoma (YORCC): a registry-based analysis of incidence trends

Wassim Daoud Khatoun

Abstract 77

Clinical predictors of local and atypical site recurrence after partial and radical nephrectomy for localized renal cell carcinoma

Rebecca Sager

Abstract 78

Dietary fructose intake and tumoral fructose-metabolism gene expression in metastatic renal cell carcinoma treated with immune checkpoint blockade

Antonio Ocejo

Abstract 79

Renal Cell Carcinoma Among Native American Patients in Oklahoma: A Single-Institution Experience From an NCI-Designated Cancer Center

Jafer Raza

Abstract 80

Real-world outcomes and clinicogenomic factors associated with response to tivozanib: a multi-center study

Jadon Fann

Abstract 81

Tumor-informed circulating tumor DNA monitoring in fumarate hydratase–deficient renal cell carcinoma

Antonio Ocejo

Abstract 82

Near-universal active surveillance for small renal mass patients: A novel 12-year clinical experience

Eric Kauffman

Abstract 83

Preclinical evaluation of LNK001: Stringent AND-gate fidelity and potent efficacy of a dual-antigen CAIX/ENPP3 CAR T cell therapy for clear cell renal cell carcinoma

Mark Wallet

Abstract 84

Phase 3 study to assess the safety and efficacy of 177Lu-girentuximab in advanced, relapsed or recurrent ccRCC (LUTEON; NCT07197580)

Sumanta Pal

Abstract 85

Phase 3 LITESPARK-033 (NCT07227402) study of belzutifan plus zanzalintinib versus cabozantinib for recurrent clear cell renal cell carcinoma during or after adjuvant anti–PD-(L)1 therapy

Toni K. Choueiri

Abstract 86

SPARCC: A single arm phase 2 study of sasanlimab, palbociclib and axitinib in metastatic renal cell carcinoma (NCT07123090).

Prateek Khanna

Abstract 88

PEAK-1 (NCT07011719): a randomized, double-blind, active-control phase 3 trial of casdatifan and cabozantinib versus placebo and cabozantinib in patients with advanced clear cell renal cell carcinoma

Toni K Choueiri

Abstract 91

Developing a Platform for Human Translational Immunology Scientific Discovery in Kidney Cancer

Julia M Walker

Abstract 93

A Decade of Decline: Cytoreductive Nephrectomy Utilization in Metastatic Renal Cell Carcinoma Before and After the CARMENA Trial

Fumika Sano

Abstract 94

NPRL2 Loss Promotes Immunosuppression via Transcription of HIF1ɑ Variants and Glycolytic Reprogramming in Renal Cell Carcinoma

Hongchao He

Abstract 96

Clinical Utility of Tumor-Informed Circulating Tumor DNA for Disease Monitoring in Localized and Metastatic Renal Cell Carcinoma

Syed Saqib Balkhi

Abstract 97

Risk-Adapted Pembrolizumab Dosing Schedule to Mitigate Financial and Time Toxicity in Adjuvant Clear Cell Renal Cell Carcinoma

Syed Saqib Balkhi

Abstract 98

PRMT3 Promotes Clear Cell Renal Cell Carcinoma Growth Through Distinct Metabolic and Tumor Microenvironment Regulatory Mechanisms

Xingdi Ma

Abstract 99

Stabilin-1+ Tumor Endothelium Organizes a Perivascular Regulatory T-Cell Niche in Renal Cell Carcinoma

Yuexin Xu

Abstract 100

Older Statins Reduce Metastatic Potential in ccRCC: Mechanistic Validation of SIM (Selective Inhibitor of Metastasis) Development

Lily Wu

Abstract 101

Profilin-1 Promotes Chromophobe Renal Cell Carcinoma

Kaylee Montanari

Abstract 103

A Novel Mitochondrial DNA-Based Spatial Assay in Renal Cell Carcinoma Reveals Immune Exclusion of Mitochondrially Mutated Tumor Clones

Rachel Saxe

Abstract 104

Real-World Clinical Outcomes Among Renal Cell Carcinoma (RCC) Patients Following Nephrectomy in the Current Immuno-Oncology Era

Randall Lee

Abstract 105

KEAP1/NRF2 Pathway Somatic and Germline Mutations in RCC

Nicole Rittenhouse

Abstract 107

Host RNA Sequencing Identifies Reproducible Intratumoral Microbial Signals Across ccRCC Datasets

Jun Yang

Abstract 109

Hyperglycemia and Antihyperglycemic Medication Escalation Following Belzutifan in Renal Cell Carcinoma

Nonna Shakhnazaryan

Abstract 110

Patterns and Predictors of Recurrence Following Partial Nephrectomy for High-Grade Renal Cell Carcinoma

Rebecca Sager

Abstract 113

Metabolic Dysfunction Trajectory and the Risk of Clear Cell Renal Cell Carcinoma Among Individuals with Type 2 Diabetes Mellitus: A Large-Scale Real-World Cohort Study

Erick Mboya

ABSTRACT BOOK

Kidney Cancer Research Summit

July 23–24, 2026 – Boston, MA

Click the image above to download the Abstract Book.
Updated 07.22.26